Home - Protheragen

AVAILABLE PROJECTS

Program	Indication	Target
Antibody Therapy
Antibody Product Portfolio	Cancer	Multiple targets
ANTIGN-109	Cancer	GnRHR
ANTICA-201	Cancer	CA215
CD3XCD20 bsAb	Lymphomas	CD3; CD20
Anti-MUC1-Ab	Solid tumor	MUC1
CD3xBCMA-bsAb	Multiple myeloma	CD3; BCMA
Anti-CD40-7409	Cancer	CD40
BioLink018	Non-Hodgkin lymphoma	CD79B
Anti-CD137-6051	Cancer	CD137
IGY-110	Covid-19	Spike proteins
Anti-LAG3 mAb	Cancer	LAG3
OX40-Ab	Cancer	OX40
A1801 ADC	Breast cancer; Melanoma	GPNMB
PMB-104	Asthma	Immunoglobulin E
PMB-107	Solid tumor	GARP/LAP-TGFβ1 complex
PBI-108	Solid tumor	PD-1 and Siglec-15
PMB-109	Asthma	TSLP
PMB-131	IgA nephropathy	MASP-2
PBI-203	Solid tumor	PD-L1 and VEGF
PBI-204	Sepsis	Adrenomedullin
PBI-205	Solid tumor	PD-1 and PD-L1
PMB-211	Fibrosis	CTGF
AB0017	Hemophilia	TFPI
AB0061	Hematologic malignancies	CD3; CD19
BI0106 ADC	Solid tumor	Trop-2
ADC0320 ADC	Cancer	Tissue factor
SP0306 ADC	Inflammatory bowel disease	IL23; TL1A
BI0201 ADC	Solid tumor	HER2; Trop-2
BI0107 ADC	Acute myeloid leukemia	CLEC12A
BC0001 Dual-payload ADC	Cancer	EGFR
BC0002 Dual-payload ADC	Cancer	HER2
BC0003 Dual-payload ADC	Solid tumor	Trop-2
BI0109 ADC	Solid tumor	B7H4
BI0110 ADC	Solid tumor	Claudin 6
BI0112 ADC	Solid tumor	FGFR2b
SP0901 ADC	Cancer	CAIX; EGFR
Protein Therapy
APD-IL10	Solid tumor	IL-10; PD-1
P75NEURO	Neurological diseases	p75NTR (NGFR)
P11	Type 2 diabetes	GLP-1 receptor
Angiocidin	Acute myeloid leukemia	Death receptor 6
TT-173	Surgical bleeding and trauma
ROD-16	Hyperoxaluria
BioLink001	Solid tumor	IL-15
JZ-603	Allergic asthma; Allergic rhinitis	IgE
PepTRx anti-HIV	AIDS	HIV proteins
AP0025	NASH; MASH; SHTG	FGF21
CD001 Fusion Protein	Cancer	PD-1; IL-21
AP-26 Fusion Protein	Solid tumor	PD-1; IL-2
BioLink1052 Fusion Protein	Type 2 diabetes, Obesity, etc	FGF21; GLP-1
CD009 Fusion Protein	Solid tumor	PD-L1; IL-10
Oncolytic Virotherapy
RV-scFv-PDL1	Cancer	PD-L1
OV-FV-01	Cancer	Confidential
BS001	Cancer
Small Molecules
IVW-1001	Dry eye disease	TRPM8
Polyoxygenated Cyclohexene Compound 4	Pain	Nav1.7
PPM-100	Cancer	IKZF1/3
Fascin Inhibitor	Cancer	Fascin
Resveratrol (Micellar)	Alzheimer’s disease	SIRT1
NMMHC IIA Inhibitors	Thrombosis	NMMHC IIA
VISTA Agonist	Psoriasis	VISTA
Berbamine Analogues	(+)ssRNA virus infections	TRPML
Intravenous Anesthetics	Anesthesia	GABA(A) receptor
Water-soluble Taxanes	Cancer	Tubulin
CQ-527	Cancer	Tubulin
FHND41	NSCLC	EGFR
BioLink1006	Metastatic cancer	EGFR
BioLink2018	B-cell lymphomas	BTK
BioLink2020	Solid tumor	FGFR1-3
BioLink2022	Heart failure	PDE9
BioLink2024	Inflammatory diseases	NLRP3
FHND91	Multiple myeloma	Proteasome
FHND71	Solid tumor	RET
CA0078	Osteoarthritis; Psoriasis	JAK
IN1605	Autoimmune diseases, Inflammatory diseases, etc	MyD88
PKY001	Solid tumor	YAP/TEAD
Cell Therapy
Double Negative T Cells	Acute myelocytic leukemia	Multi-target
Anti-BCMA CAR-T Cell	Multiple myeloma	BCMA
Anti-GPRC5D CAR T-cell	Multiple myeloma	GPRC5D
GCC-CART	Metastatic colorectal cancer	GUCY2C
EDB-TCR-T	Solid tumor	Fibronectin extra domain B
duraCAR-T71	Cancer	Claudin 18.2
TCR-T012	Cancer	WT1
TCR-T013	Cancer	EBV
TCR-T014	Cervical cancer	HPV-16
TCR-T015	Lung cancer; Pancreatic cancer	KRAS
TCR-T016	Cancer	NY-ESO-1
Gene Therapy
RNA4TNBC	Triple-negative breast cancer	MIR34A; MIR21
Others
IVIEW-1201	Conjunctivitis